Louis Globe-Democrat of August 1886: “He has roamed the block all morning like a boy who had lost his marbles.” ![]() An early citation of this figurative usage is found in the St. To play was always to run the risk of losing all one’s marbles and the result might easily be anger, frustration, and despair. This American phrase arose in the late 1800s, probably from the game of marbles, which was common at the time. ![]() In any case, your mind isn’t functioning as it should. When you lose your marbles, you’ve lost your mind, or gone insane, or part of your brain is missing.
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